by Franco Cavaleri BSc PhDc (Experimental Medicine)
Original post: November 15, 2017
The best builders’ dietary program must keep dietary protein at a level that serves anabolism (building new tissue), which means consuming higher amounts of protein than the strict medical ketogenic diet allows for. Adding the exogenous ketones helps preserve protein for anabolism and prevent lean tissue catabolism (breaking down complex molecules and releasing energy). Using KETOBA twice per day maintains a buffer zone of serum ketones despite dietary choices. This allows for incremental protein intake to meet higher demands created by intense exercise while maintaining functional serum ketone levels that would otherwise be reduced by the introduction of a glucogenic (contributing to glucose production) protein source.
One step further: adding short-chain fatty acids (SCFA) like butyrate/butyric acid (BA) with the ketone body, like β-hydroxybutyrate (BHB), synergises the exogenous ketone serving as a β-oxidation trigger. BA supports the effects of the exogenous ketone by contributing to serum levels from endogenous sources and does so without gastrointestinal (GI) distress. This distress is commonly associated with high dose oral ketone and/or Medium Chain Triglyceride (MCT), and counters performance and immunity by disrupting probiotic stability and interfering with resorption of electrolytes and water.
Dehydration and electrolyte depletion are an athlete’s worst nightmare, compromising muscle mass strength and endurance. GI distress impairs exercise performance, and doesn’t support optimal health and immunity either. BA is a SCFA that facilitates electrolyte and water reabsorption and helps balance probiotic culture in the colon. Colonocytes, epithelial cells in the colon, use BA as an energy source and a down-regulator of inflammation.
In addition BA delivers a pharmacology that supports insulin efficiency and blood sugar management, allowing the ketone (BHB) an opportunity to surface in serum as a primary energy (ATP) substrate. BA also supports cognitive performance and cardiovascular health. The name KETOBA is formed from ketone (BHB) coupled with BA, the short-chain fatty acid. Hence KETO-BA.
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