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Writer's pictureFranco Cavaleri, BSc, Ph.Dc

Organophosphate Pesticide Toxicity - Insulin resistance and diabetes

Updated: Oct 16, 2023

Is this the underlying cause of epidemic proportion of diabetes and obesity in North America?


Blended excerpts from Potential Within A Guide to Nutritional Empowerment

Authored by Franco Cavaleri ISBN 0-9731701-0-7

Original post: February 24, 2011



This article is composed of multiple excerpts to result in tone and content shifts and reference numbering that may be out of order.


Organophosphate Pesticide Toxicity - Insulin resistance and diabetes

Studies of Mexican communities such as Tescopaco confirm that these facts are much more than probable. A study done by Elizabeth Gillette et al in 1994 confirmed the dangers of unregulated pesticide use. The rich soils of the Mexican Yaqui Valley seeded a successful farming community that proliferates today. Pesticide application here has become profuse and unregulated. In 1998 the results of the Gillette study were published in a peer-reviewed journal.


The valley’s population experienced twice the birth defects and infant deaths of communities in the immediate outskirts. The valley girls’ breast development was well under way at age seven—equivalent to young girls of age 12 in the outskirts. Breast development is estrogen-dependent (60). The same study revealed that the young men of the valley were physically immature for their age, with problems that included the late development of gonads.


The Gillette findings reveal that exposure to these toxins with the intensity that the Mexican locals experienced can have horrific consequences. North Americans might not be exposed to the degree that these Mexican communities are, but the small, frequent, multiple increments we receive from a variety of sources do reach considerable levels. For an infant or child this can lead to severe immediate consequences and repercussions that might appear later in life when compounded by other stresses.


The solution to the coffee problem, if you must indulge in the beverage, is to choose organic, freshly ground beans. Drink one cup before exercise to facilitate the burning of fat as an energy source during activity, sparing muscle glycogen and saving muscle from catabolism. A cup of coffee with a meal can improve dietary-induced thermogenesis (DIT), assisting the oxidation or “burning” of excess dietary fat (61).


Caffeine also reduces the threshold for endorphin secretion, enhancing pain tolerance and performance potential (62). Moreover, the stimulant appears to increase lipolysis or fat breakdown independent of a meal (63). These coffee facts shed light on the value of eating organic as much as possible. Other factors contribute to the effects of caffeine in the body today that might not have been issues in the past. Contraceptive pills can boost the half-life of caffeine, and estrogen-replacement therapy in postmenopausal women enhances caffeine’s stimulatory influence to the point where in some individuals its consumption becomes intolerable (64). Cimetidine, a common drug employed to combat excess stomachacid secretions, also interferes with the clearance of caffeine from blood (65).


If you take these drugs, you might have noticed a newly developed sensitivity to coffee or caffeine-rich teas. Interestingly the amplified sensitivity and the likely increment of free fatty-acid mobilization that this factor might induce could possibly contribute to the risk of insulin resistance….




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